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Patients receiving the combination spent an average of 4 months longer living in the community. Patients receiving the combination therapy also spent less time in the severe stages of AD 3. In the lifetime time horizon, the number of months in an institution was estimated at In the previous study, the difference in the mean amount of time spent in an institution over the 3-year period was more substantial, with an estimated In another study using data from the LTOC study discussed earlier modeled over a time horizon of 7 years, combination memantine and ChEI was associated with a mean time to nursing home admission of 5.

   
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