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Monoamine oxidase inhibitors and potential for interaction with adrenergic and serotonergic agents. ZYVOX is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. It is critical that specific Gram-negative therapy be initiated immediately if a concomitant Gram-negative pathogen is documented or suspected. Community-acquired pneumonia caused by Streptococcus pneumoniae, including cases with concurrent bacteremia, or Staphylococcus aureus methicillin-susceptible isolates only. Complicated skin and skin structure infections, including diabetic foot infections, without concomitant osteomyelitis, caused by Staphylococcus aureus methicillin-susceptible and -resistant isolates, Streptococcus pyogenes, or Streptococcus agalactiae.
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