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Inhibits reuptake of serotonin, causes adrenoreceptor subsensitivity, acts as a 5HT 2a receptor antagonist and induces significant changes in 5-HT presynaptic receptor adrenoreceptors. Trazodone also significantly blocks histamine H 1 and alpha1-adrenergic receptors. Well absorbed. Data from a limited number of patients studied suggest that trazodone may be beneficial in decreasing symptom frequency and severity, as well as decreasing use of adjunctive medications, in patients with aggression or agitation associated with dementia. Data from a meta-analysis of a limited number of controlled trials in patients with and without comorbid conditions including Alzheimer disease, depression, and opioid dependence suggest that trazodone may be beneficial in the short-term to decrease number of awakenings and improve sleep quality in patients with insomnia. Insomnia alternative agent off-label use : Oral: Immediate release: Usual dose: 50 mg to mg at bedtime Yi
It labels chemicals in the current that may be considered in people with depression. Trazodone is linear to find major depressive disorder.
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Enhances neuronal differentiation of mouse and human neural progenitor cells. Antidepressant and neuroprotectant. Trazodone hydrochloride is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris. The technical data provided above is for guidance only.
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Anti-Inflammatories Supplements. It it used to treat and manage certain types of depression, anxiety, fear-based aggression and behavioral disorders in dogs. If your pet suffers from or has been diagnosed with a behavioral disorder, your veterinarian may prescribe an antidepressant type medication such as Trazodone.
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