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It is used to treat Parkinson's disease and conditions caused by too much of the hormone, prolactin. For Parkinson's disease, bromocriptine works by behaving like dopamine, a chemical in the brain, which is involved in producing the symptoms of this disease. Bromocriptine may be used alone or with levodopa to reduce symptoms of Parkinson's disease. For conditions associated with too much prolactin, bromocriptine works by blocking the release of prolactin from the pituitary gland in the brain. Bromocriptine is used to treat acromegaly overproduction of growth hormone causing unusual enlargement of the hands, jaw, and feet by decreasing the production of growth hormone. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Bromocriptine is a sympatholytic D2-dopamine agonist that has been approved for the treatment of type 2 diabetes. Based on animal and human studies, timed bromocriptine administration within 2 h of awakening is believed to augment low hypothalamic dopamine levels and inhibit excessive sympathetic tone within the central nervous system CNS, resulting in a reduction in postmeal plasma glucose levels due to enhanced suppression of hepatic glucose production. Bromocriptine also reduces fasting and postmeal plasma free fatty acid FFA and triglyceride levels. Because of its multifactorial pathogenesis, restoration of normoglycemia is difficult to achieve and requires multiple antidiabetic medications that have different mechanisms of action and can be used in combination to produce an additive effect 1, 2. Therefore, the development of antidiabetic agents that have novel mechanisms of action and can be used in combination with currently approved medications for the treatment of type 2 diabetes is highly desirable. Type 2 diabetic patients are at high risk for atherosclerotic cardiovascular complications 3.
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Laura (taken for 3 to 5 years) 29.03.2016
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