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The aggregation of platelets in patients with vascular disease can cause ischaemic events such as myocardial infarction and stroke. Therefore, antiplatelet drugs have an important role in preventing these events.
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DOI: Consequently, health authorities and health insurance agencies need to take full advantage of the availability of generics in order to continue funding comprehensive health care particularly in Europe.
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Symptoms of an overdose include tachycardia, agitation, dysarthria, decreased consciousness, and coma. Drugs or agents that increase the activity of the enzyme CYP1A2, notably tobacco smoke, may significantly increase hepatic first-pass clearance of olanzapine; conversely, drugs which inhibit CYP1A2 activity examples: ciprofloxacin, fluvoxamine may reduce olanzapine clearance.
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