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From Serophene is a fertility drug, used to stimulate FSH and LH production and hereby the ovaries to produce eggs in ovarian disorders. Infertility, Infertility in women, Polycystic ovary syndrome. Serophene is an non-steroid anti-estrogen. Mechanism of its action consists in a specific binding with receptor for estrogen in ovary and hypophis. In patients with low estrogen levels in organism it causes estrogen effect and in ones with high estrogen levels it causes anti-estrogen effect. Its small doses increase secretion of gonadotropins prolactin, Follicle stimulating hormone, FSH and interstitial cell-stimulating hormone, stimulates ovulation; in large doses slows secretion of gonadotropins.
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Ovulation is the monthly process whereby the female reproductive system produces a mature egg. During ovulation, the brain's pituitary gland releases two hormones: follicle stimulating hormone FSH and luteinizing hormone LH. Together, these hormones are known as gonadotropins. FSH acts as a 'messenger' sent by the pituitary gland to stimulate the development of follicles in the ovaries, each of which will contain one egg. LH is responsible for triggering the release of the egg ovulation.
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