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The manufacturer and some clinicians states that IV acyclovir should be given for days; the CDC states that IV acyclovir should be given for days or until clinical improvement occurs and then an oral antiviral agent should be substituted to complete at least 10 days of therapy. Therapy can be switched to oral acyclovir mg 4 times daily after defervescence if there is no evidence of visceral involvement. Because acyclovir is removed by hemodialysis, the manufacturer recommends that patients undergoing hemodialysis receive a supplemental oral dose of the drug immediately after each dialysis period.
Simone (taken for 2 to 7 years) 08.04.2018
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